What is Interstitial Cystitis?
Interstitial cystitis, also known as Bladder Pain Syndrome (IC/BPS), is a chronic condition characterised by recurring discomfort or pain in the bladder and surrounding pelvic region. Unlike typical bladder infections, IC isn’t caused by bacteria and doesn’t respond to antibiotics. Think of your bladder as a balloon – in healthy individuals, this balloon can comfortably fill and empty without distress. However, in IC patients, the protective layer of the bladder (called the glycosaminoglycan or GAG layer) becomes compromised. This is like having tiny tears in the balloon’s surface, allowing irritating substances in urine to penetrate the bladder wall and trigger inflammation, pain, and urinary symptoms.
Patients often describe feelings of pressure, discomfort, and pain that range from mild to severe. The condition can significantly impact quality of life, affecting sleep patterns, social activities, and even intimate relationships. Women are more commonly affected than men, though men can certainly develop IC as well. The onset can be gradual or sudden, and symptoms often fluctuate, with periods of flares and remission
Introduction to Bladder Health
Before diving into interstitial cystitis (IC), let’s establish what healthy bladder function looks like:
- 4-6 daily urinations plus one nighttime void (ideally sleeping through)
- 300-500ml per void, with capacity to hold more when needed
- Pale urine color (think chardonnay, not beer)
- Pain-free filling and emptying
- Natural urge progression without sudden urgency
- Strong, consistent flow
The Histamine-IC Connection
I have noticed an interesting connection between interstitial cystitis and histamine intolerance. This connection might explain why many patients experience overlapping symptoms and react to similar triggers.
Mast Cells
Your bladder wall contains specialised cells called mast cells, which act as tiny storage units for various chemical messengers, including histamine. When triggered, these cells release their contents, potentially causing:
- Inflammation in the bladder wall
- Increased sensitivity to normal filling
- Altered bladder muscle function
- Changes in nerve sensitivity
- Modified blood flow to bladder tissues
This explains several common IC characteristics:
- The episodic nature of symptoms
- Effectiveness of heat therapy (which can stabilise mast cells)
- Normal medical test results despite significant symptoms
Trigger Foods and Environmental Factors
Common Bladder Irritants:
Many IC trigger foods overlap with high-histamine foods. Key items to avoid include:
- Alcoholic beverages
- Caffeinated drinks (coffee, tea)
- Carbonated beverages
- Acidic foods (citrus, tomatoes)
- Spicy foods (hot peppers, chili)
- Fermented foods (sauerkraut, pickles)
- Artificial sweeteners
- MSG
- Chocolate
- Vinegar-based condiments
Environmental and Lifestyle Triggers
- Stress
- Sleep disruption
- Circadian rhythm disturbances
- Hormonal fluctuations
Natural Support Strategies
Just a few of the gems.
Crateva magna
A beautiful herb that has an affinity for the bladder, and acts as a bladder antiinflammatory and tonic specific for cystitis
L-arginine (1,500 mg/day)
Improves symptoms by increasing urinary nitric oxide synthase activity
Approximately 50% of patients report improvement
Omega-3 fatty acids
Alpha lipoic acid
Quercetin (a natural antihistamine and mast cell stabiliser)
Anti-inflammatory Support
DAO Enzyme
Diamine oxidase is an enzyme that helps your body break down histamine
Lifestyle Modifications
Dietary Approaches
- Implementation of low-histamine diet
- Food journaling to identify personal triggers
- Proper hydration without overhydrating
Stress Management
- Regular sleep schedule
- Stress reduction techniques
- Heat therapy
- Gentle exercise
Understanding Flares
During severe episodes, some patients may experience blood in urine due to:
- Intense mast cell activation
- Increased blood vessel permeability
- Local inflammation
- These symptoms typically resolve as the episode settles
Understanding the connection between histamine intolerance and IC opens new avenues for treatment and management. By addressing both conditions simultaneously, many patients find more effective relief than treating either condition in isolation.
Remember that healing is individual, and what works for one person may not work for another. Working with healthcare providers who understand both conditions can help develop a personalised treatment approach.
As a naturopath practicing in the beautiful Perth Hills area of Kalamunda, I’m passionate about helping people find natural solutions to complex health challenges like IC. If you’re struggling with bladder issues, histamine intolerance, or any other health concerns, I’d love to work with you to develop a personalised treatment plan that addresses your unique needs and circumstances.
Understanding conditions like IC can feel overwhelming, but you don’t have to navigate this journey alone. Whether you’re just starting to experience symptoms or have been dealing with bladder issues for years, I’m here to help you find relief through natural, holistic approaches.
To book a consultation with me and start your healing journey, simply click here!